anti- ZEB1 antibody

Product Description

anti- ZEB1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Acts as a transcriptional repressor. Inhibits interleukin-2(IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition(EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box(5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs. The calculated molecular weight of ZEB1 is 124 kDa, but the post phosphorylation of protein is about 190-210 kDa. This is a rabbit polyclonal antibody raised against part of the full length of ZEB1 of human..

Immunogen: zinc finger E-box binding homeobox 1

Synonyms: AREB6, BZP, DELTA EF1, delta EF1,, Negative regulator of IL2, NIL 2 A, NIL 2 A zinc finger protein, NIL 2A, NIL2A, TCF 8, TCF8, Transcription factor 8, ZEB, ZEB1, ZFHEP, ZFHX1A

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IP,IHC

Recommended dilution: WB: 1:500-1:5000; IP: 1:200-1:2000?IHC: 1:500-1:5000

Image 1: Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab09620(ZEB1 Antibody) at dilution of 1:1000

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Image 4: MCF7 cells were subjected to SDS PAGE followed by western blot with FNab09620(ZEB1 antibody) at dilution of 1:500

Gene ID: 6935

Research Area: Metabolism

Uniprot ID: P37275