anti- ZFP36L2 antibody

Product Description

anti- ZFP36L2 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: mRNA-binding protein that plays a key role in self-renewal of erythroid cells in response to glucocorticoids. Specifically binds to the AU-rich element(ARE) in the 3'-UTR of target mRNAs, promoting their deadenylation and degradation(PubMed:14981510). Specifically expressed in burst-forming unit-erythroid(BFU-E) progenitors in response to glucocorticoids and acts as a negative regulator of erythroid cell differentiation: promotes self-renewal of erythroid cells by binding mRNAs that are induced or highly expressed during terminal erythroid differentiation and promotes their degradation, preventing erythroid cell differentiation. Down-regulated during erythroid differentiation from the BFU-E stage, stabilizing mRNAs required for terminal differentiation(By similarity)..

Immunogen: zinc finger protein 36, C3H type-like 2

Synonyms: BRF2, Butyrate response factor 2, EGF response factor 2, ERF 2, ERF2, Protein TIS11D, RNF162C, TIS11D, ZFP36L2

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB

Recommended dilution: WB: 1:200-1:2000

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Image 4: HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09625(ZFP36L2 antibody) at dilution of 1:500

Gene ID: 678

Research Area: Metabolism

Uniprot ID: P47974