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Product Description
anti- ZGPAT antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Transcription repressor that specifically binds the 5'-GGAG[GA]A[GA]A-3' consensus sequence. Represses transcription by recruiting the chromatin multiprotein complex NuRD to target promoters. Negatively regulates expression of EGFR, a gene involved in cell proliferation, survival and migration. Its ability to repress genes of the EGFR pathway suggest it may act as a tumor suppressor. Able to suppress breast carcinogenesis. Isoform 4: Antagonizes the transcription repression by isoform 1 by competing for the binding of the NuRD complex. Does not bind DNA..
Immunogen: zinc finger, CCCH-type with G patch domain
Synonyms: ZGPAT, ZC3HDC9, ZC3H9, KIAA1847, GPATCH6
Reactivity: Human, Mouse
Tested Application: ELISA, WB
Recommended dilution: WB: 1:500-1:5000
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Image 4: L02 cells were subjected to SDS PAGE followed by western blot with FNab09634(ZGPAT antibody) at dilution of 1:1000
Gene ID: 84619
Research Area: Metabolism
Uniprot ID: Q8N5A5
