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Product Description
anti- ZW10 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex(PubMed:11590237, PubMed:15485811, PubMed:15824131). Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum(ER); the function is proposed to depend on its association in the interphase NRZ complex which is believed to play a role in SNARE assembly at the ER(PubMed:15029241)..
Immunogen: ZW10, kinetochore associated, homolog(Drosophila)
Synonyms: HZW10, KNTC1AP, ZW10
Reactivity: Human
Tested Application: ELISA, WB
Recommended dilution: WB: 1:500-1:5000; IP: 1:200-1:2000
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Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09760(ZW10 Antibody) at dilution of 1:1000
Gene ID: 9183
Research Area: Metabolism
Uniprot ID: O43264
