ACTH (Adrenocorticotrophic Hormone) (N-Terminal) (Pituitary Marker) Recombinant Mouse Monoclonal Antibody [Clone 57]

Product Description

ACTH (Adrenocorticotrophic Hormone) (N-Terminal) (Pituitary Marker) Recombinant Mouse Monoclonal Antibody [Clone 57] is available at Gentaur for Next Week Delivery.

Product Short Name:  ACTH (Adrenocorticotrophic Hormone)

Other Names:

Product Gene Name: [ACTH]

Other Gene Names: 

Clonality:

Isotype: IgG1, kappa

Clone:

Host: Mouse

Reactivity: Human, Mouse, Rat. Expected to show a broad species reactivity.

Specifity: ACTH (same as Corticotropin) is a 39 amino acid active peptide produced by the anterior pituitary. This MAb is specific to Synacthen (aa1-24 of ACTH); does not react with CLIP (aa17-39 of ACTH). POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin. ACTH is also produced by cells of immune system (T-cells, B-cells, and macrophages) in response to stimuli associated with stress. Anti-ACTH is a useful marker in classification of pituitary tumors and the study of pituitary disease. It reacts with ACTH-producing cells (corticotrophs). It also may react with other tumors (e.g. some small cell carcinomas of the lung) causing paraneoplastic syndromes by secreting ACTH.

Purity: 

Form: 200ug/ml of Ab purified by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: 

Storage Stability:  Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application:  ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC)