MTAP (Tumor Suppressor Marker)

Product Description

MTAP (Tumor Suppressor Marker) is available at Gentaur for Next Week Delivery.

Product Short Name:  MTAP

Other Names: [S-methyl-5'-thioadenosine phosphorylase; S-methyl-5'-thioadenosine phosphorylase; S-methyl-5'-thioadenosine phosphorylase; methylthioadenosine phosphorylase; 5'-methylthioadenosine phosphorylase]

Product Gene Name: [MTAP]

Other Gene Names: [MTAP; MTAP; BDMF; MSAP; DMSFH; LGMBF; DMSMFH; c86fus; HEL-249]

Clonality:

Isotype: IgG1, kappa

Clone: [rMTAP/1813]

Host: Mouse

Reactivity: Human

Specifity: Recognizes a protein of 31kDa, which is identified as MTAP (5'-deoxy-5'-methylthioadenosine phosphorylase). It catalyzes the reversible phosphorolysis of methylthioadenosine, which is important in polyamine metabolism and for the salvage of adenine and methionine. The gene encoding MTAP is linked to the tumor suppressor gene, p16INK4A. Deficient levels of MTAP can occur in cancers primarily through co-deletion of the MTAP gene and the p16INK4A gene. Cells expressing MTAP and possessing adenine salvage pathway activity may be less susceptible to malignancy due to growth-inhibitory actions of agents (e.g. antifolates), whose mechanism of action, in part, involves this de novo purine pathway.

Purity:  Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: 

Storage Stability:  Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application:  Immunohistochemistry (IHC) Paraffin