SOX2 (Embryonic Stem Cell Marker)

Product Description

SOX2 (Embryonic Stem Cell Marker) is available at Gentaur for Next Week Delivery.

Product Short Name:  SOX2

Other Names: [transcription factor SOX-2; Transcription factor SOX-2; transcription factor SOX-2; SRY-box transcription factor 2]

Product Gene Name: [SOX2]

Other Gene Names: [SOX2; SOX2; ANOP3; MCOPS3]

Clonality:

Isotype: IgG1, kappa

Clone: [rSOX2/1792]

Host: Mouse

Reactivity: Human, Mouse

Specifity: SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Reportedly, SOX2 is associated with aggressive phenotypes of breast, head and neck, gastric, colorectal, bladder, and small cell lung cancers. However, SOX2 is expressed in a high percentage of lung squamous cell carcinomas and has been shown to be an independent favorable prognostic marker.

Purity:  Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Concentration: 

Storage Stability:  Antibody with azide: store at 2 to 8 degree C.
Antibody without azide: store at -20 to -80 degree C.
Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Tested Application:  ELISA (EIA), Immunohistochemistry (IHC) Paraffin