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Product Description
CREB Blocking Peptide is available at Gentaur for Next week delivery.
Short Description: 50 ug Blocking Peptide for CREB polyclonal antibody (3360R-100).
Formulation: 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA and 0.02% thimerosal.
Application and Usage: Transcription factor CREB binds the cAMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth or neurotrophic factors. Protein kinase A and the calmodulin-dependent protein kinase CaMKII stimulate CREB phosphorylation at Ser133, a key regulatory site controlling transcriptional activity. Phosphorylation at Ser133 is also mediated by p44/42 MAP kinase, p90RSK, p38 MAP kinase and MSK1. CREB appears to play an important role in learning and memory in both flies and mice.
Handling: The peptide solution should be gently mixed before use.
Research Use: For Rersearch Use Only! Not to be used in humans.
Antibody Target: CREB
Western Blot (WB): Verified
Gene ID: 81646
NCBI Accession: EDL98880
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