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  • Anti-Phosphorilated Histone H2AX

    • Anti-Phosphorilated Histone H2AX | Gentaur

    Gentaur

    €0.00
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    SKU:
    03-4418-APC-100-GEN
    Availability:
    24/48 H for Stock Items & 1 or 2 weeks for Production Items
    Weight:
    1 KGS
    Price:
    Contact info@gentaur.com for pricing

    Product Description

    Anti-Phosphorilated Histone H2AX

    Quality Level

    100

    biological source

    mouse

    antibody form

    affinity purified immunoglobulin

    clone

    JBW301, monoclonal

    species reactivity

    vertebrates

    packaging

    antibody small pack of 25 μg

    manufacturer/tradename

    Upstate®

    technique(s)

    ChIP: suitable
    immunocytochemistry: suitable
    immunofluorescence: suitable
    immunohistochemistry: suitable
    western blot: suitable

    isotype

    IgG1

    NCBI accession no.

    NP_002096

    General description

    Histone H2A is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H2A is involved with the structure of the nucleosomes of the ′beads on a string′ structure.

    Specificity

    Recognizes Histone H2A.X phosphorylated at Ser139.

    Immunogen

    peptide (C-KATQA[pS]QEY) corresponding to amino acids 134-142 of human histone H2A.X

    Application

    Anti-phospho-Histone H2A.X (Ser139), clone JBW301 is a well published Mouse Monoclonal Antibody validated in ChIP, ICC, IF, WB. This purified mAb is highly specific for phospho-Histone H2A.X (Ser139) also known as H2AXS139p.
    Research Sub Category
    Histones
    Research Category
    Epigenetics & Nuclear Function
     
    Additional Referenced Applications:
     
    Immunohistochemistry Analysis: A representative lot detected Histone H2A.X (pSer139) in RNF168-WT and RNF 168-SA/SEKI mice lung tissue sections (Paraffin). (Xe, X., et al. (2015) Nat. Cell Biol. 20 (3); 320-331).
    Chromatin Immunoprecipitation, see Meier, Andreas, et al. EMBO J., 26: 2707-18 (2007) in technical information tab.

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