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  • Anti-TREM2 Antibody

    • Anti-TREM2 Antibody | Gentaur

    Gentaur

    €0.00
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    SKU:
    544-MBS242024-GEN
    Availability:
    24/48 H for Stock Items & 1 or 2 weeks for Production Items
    Weight:
    1 KGS
    Price:
    Contact info@gentaur.com for pricing

    Product Description

    Anti-TREM2 Antibody

    Quality Level

    100

    Biological source

    rat

    Antibody form

    purified antibody

    Antibody product type

    primary antibodies

    Clone

    78, monoclonal

    Species reactivity

    human, mouse, rat

    Technique(s)

    flow cytometry: suitable
    immunocytochemistry: suitable
    immunoprecipitation (IP): suitable
    inhibition assay: suitable
    western blot: suitable

    TREM-2, also known as Triggering receptor expressed on myeloid cells 2 or Triggering receptor expressed on monocytes 2, and encoded by the gene Trem2/Trem2a/Trem2b/Trem2c, is a protein that forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells.

    TREM-2 may also have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. TREM-2 is localized to the cell membrane and is a single pass membrane protein.

    TREM-2 is expressed in immune cells such as microglia and monocytes but the expression varies depending upon the exact tissue and location within the tissue. Defects in TREM-2 may be associated in humans with frontotemporal dementia, Nasu-Hakola disease, and recently an increase risk of Alzheimer′s disease.

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