Product Description
Recombinant Chicken Collagen alpha-1 (XII) chain (COL12A1), partial is available at Gentaur for Next week Delivery.
Gene Name: COL12A1
Alternative Names : Fibrochimerin
Expression Region : 139-311aa
AA Sequence : DLVFLVDGSWSVGRNNFRYILDFMVALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYFRRSDLLDAIKRIPYKGGNTMTGEAIDYLVKNTFTESAGARKGFPKVAIVITDGKAQDEVEIPARELRNIGVEVFSLGIKAADAKELKLIASQPSLKHVFNVANFDGIVDIQNEI
Sequence Info : Partial
Tag Info : N-terminal 6xHis-tagged
Theoretical MW : 21.3 kDa
Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Endotoxin Level : Not tested-
Biological Activity : Not tested
Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
Research Area : Others
Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance : Type XII collagen interacts with type I collagen-containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix.
Function : Type XII collagen interacts with type I collagen-containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix.
Involvement in disease :
Subcellular location : Secreted, extracellular space, extracellular matrix
Protein Families : Fibril-associated collagens with interrupted helices (FACIT) family
Tissue Specificity : Type XII collagen is present in tendons, ligaments, perichondrium, and periosteum, all dense connective tissues containing type I collagen.
Paythway :
Uniprot ID : P13944