Product Description
Recombinant Fruit fly Accessory gland-specific peptide 70A (SP) is available at Gentaur for Next week Delivery.
Gene Name: SP
Alternative Names : Paragonial peptide B Sex peptide Short name: SP
Expression Region : 20-55aa
AA Sequence : WEWPWNRKPTKFPIPSPNPRDKWCRLNLGPAWGGRC
Sequence Info : Full Length of Mature Protein
Tag Info : Tag-Free
Theoretical MW : 4.3 kDa
Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Endotoxin Level : Not tested-
Biological Activity : Not tested
Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
Research Area : Others
Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance : Male seminal protein which triggers short- and long-term post-mating behavioral responses (PMR) in female Drosophila (PubMed:3135120, PubMed:19249273, PubMed:20308537, PubMed:19793753, PubMed:15694303, PubMed:24089336). Binds initially to sperm where it is later cleaved to release an active peptide within the female reproductive tract. Signals via the sex peptide receptor (SPR) in female flies; may also act via other receptors (PubMed:20458515, PubMed:20308537, PubMed:24089336). Moderates the activity of distinct neuronal circuitries in the female genital tract to promote specific PMRs including: enhanced ovulation, increased egg laying rate, increased feeding/foraging rate, induced antimicrobial peptide synthesis, reduced mating receptivity, reduced day-time sleep and reduced lifespan in multiple mated females (PubMed:3135120, PubMed:15694303, PubMed:19249273, PubMed:19793753, PubMed:24089336).
Function : Male seminal protein which triggers short- and long-term post-mating behavioral responses (PMR) in female Drosophila
Involvement in disease :
Subcellular location : Secreted
Protein Families : Drosophila sex peptide family
Tissue Specificity : Main cells of the accessory glands of males (paragonial gland).
Paythway :
Uniprot ID : P05623