Recombinant Human 78KDA glucose-regulated protein (HSPA5), partial

Product Description

Recombinant Human 78KDA glucose-regulated protein (HSPA5), partial is available at Gentaur for Next week Delivery.

Gene Name: HSPA5

Alternative Names : Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78Heat shock 70KDA protein 5Immunoglobulin heavy chain-binding protein;BiP

Expression Region : 25-293aa

AA Sequence : EDVGTVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNPENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAMVLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIAYGLDKREGEKNILVFDLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRVMEHFIKLYKKKTGKDVRKDNRAVQKLRREVE

Sequence Info : Partial

Tag Info : N-terminal 6xHis-tagged

Theoretical MW : 33.6 kDa

Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Endotoxin Level : Not tested-

Biological Activity : Not tested

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Others

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Probably plays a role in facilitating the assbly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate.

Function : Plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate (By similarity).

Involvement in disease : Autoantigen in rheumatoid arthritis.

Subcellular location : Endoplasmic reticulum lumen, Melanosome, Cytoplasm

Protein Families : Heat shock protein 70 family

Tissue Specificity :

Paythway : Proteinprocessinginendoplasmicreticulum

Uniprot ID : P11021