Recombinant Human Aldehyde dehydrogenase family 1 member A3 (ALDH1A3)

Product Description

Recombinant Human Aldehyde dehydrogenase family 1 member A3 (ALDH1A3) is available at Gentaur for Next week Delivery.

Gene Name: ALDH1A3

Alternative Names : Aldehyde dehydrogenase 6 Retinaldehyde dehydrogenase 3 Short name:RALDH-3 Short name:RalDH3

Expression Region : 2-512aa

AA Sequence : ATANGAVENGQPDRKPPALPRPIRNLEVKFTKIFINNEWHESKSGKKFATCNPSTREQICEVEEGDKPDVDKAVEAAQVAFQRGSPWRRLDALSRGRLLHQLADLVERDRATLAALETMDTGKPFLHAFFIDLEGCIRTLRYFAGWADKIQGKTIPTDDNVVCFTRHEPIGVCGAITPWNFPLLMLVWKLAPALCCGNTMVLKPAEQTPLTALYLGSLIKEAGFPPGVVNIVPGFGPTVGAAISSHPQINKIAFTGSTEVGKLVKEAASRSNLKRVTLELGGKNPCIVCADADLDLAVECAHQGVFFNQGQCCTAASRVFVEEQVYSEFVRRSVEYAKKRPVGDPFDVKTEQGPQIDQKQFDKILELIESGKKEGAKLECGGSAMEDKGLFIKPTVFSEVTDNMRIAKEEIFGPVQPILKFKSIEEVIKRANSTDYGLTAAVFTKNLDKALKLASALESGTVWINCYNALYAQAPFGGFKMSGNGRELGEYALAEYTEVKTVTIKLGDKNP

Sequence Info : Full Length of Mature Protein

Tag Info : N-terminal 6xHis-tagged

Theoretical MW : 58 kDa

Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Endotoxin Level : Not tested-

Biological Activity : Not tested

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Others

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Recognizes as substrates free retinal and cellular retinol-binding protein-bound retinal. Seems to be the key enzyme in the formation of an RA gradient along the dorso-ventral axis during the early eye development and also in the development of the olfactory system

Function : NAD-dependent aldehyde dehydrogenase that catalyzes the formation of retinoic acid

Involvement in disease : Microphthalmia, isolated, 8 (MCOP8)

Subcellular location : Cytoplasm

Protein Families : Aldehyde dehydrogenase family

Tissue Specificity : Expressed at low levels in many tissues and at higher levels in salivary gland, stomach, and kidney.

Paythway :

Uniprot ID : P47895