Recombinant Human Amphiregulin protein (AREG) (Active)

Product Description

Recombinant Human Amphiregulin protein (AREG) (Active) is available at Gentaur for Next week Delivery.

Gene Name: AREG,SDGF;,AREGB

Alternative Names : AR, CRDGF

Expression Region : 101-198aa

AA Sequence : SVRVEQVVKP PQNKTESENT SDKPKRKKKG GKNGKNRRNR KKKNPCNAEF QNFCIHGECK YIEHLEAVTC KCQQEYFGER CGEKSMKTHS MIDSSLSK

Sequence Info : Partial

Tag Info : Tag-Free

Theoretical MW : 11.3 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered PBS, pH 7.4

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is between 10-15 ng/ml.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Cancer

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts.

Function : Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts.

Involvement in disease :

Subcellular location : Membrane, Single-pass membrane protein

Protein Families : Amphiregulin family

Tissue Specificity :

Paythway : ErbBsignalingpathway

Uniprot ID : P15514