Product Description
Recombinant Human Beta-defensin 4A (DEFB4A) is available at Gentaur for Next week Delivery.
Gene Name: DEFB4A
Alternative Names : Beta-defensin 2
Expression Region : 1-64aa
AA Sequence : MRVLYLLFSFLFIFLMPLPGVFGGIGDPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKCCKKP
Sequence Info : Full Length
Tag Info : N-terminal GST-tagged
Theoretical MW : 31.3 kDa
Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Endotoxin Level : Not tested-
Biological Activity : Not tested
Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
Research Area : Microbiology
Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance : Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to both human and mouse CCR6 and induce chemotactic activity of CCR6-expressing cells
Function : Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to both human and mouse CCR6 and induce chemotactic activity of CCR6-expressing cells
Involvement in disease :
Subcellular location : Secreted
Protein Families : Beta-defensin family, LAP/TAP subfamily
Tissue Specificity : Expressed in the skin and respiratory tract.
Paythway :
Uniprot ID : O15263