Recombinant Human Bone morphogenetic protein 2 (BMP2) (Active)

Product Description

Recombinant Human Bone morphogenetic protein 2 (BMP2) (Active) is available at Gentaur for Next week Delivery.

Gene Name: BMP2

Alternative Names : Bone Morphogenetic Protein 2; BMP-2; Bone Morphogenetic Protein 2A; BMP-2A; BMP2; BMP2A

Expression Region : 283-396aa

AA Sequence : QAKHKQRKRLKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVNSKIPKACCVPTELSAISMLYLDENEKVVLKNYQDMVVEGCGCR

Sequence Info : Full Length of Mature Protein

Tag Info : Tag-Free

Theoretical MW : 13.3 kDa

Storage Buffer : Lyophilized from a 0.2 ?m Filtered 10 mM NH4-HAC, pH 4.0

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The ED50 as determined by the cytolysis of MC3T3-E1 cells is less than 2 ?g/ml

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Signal Transduction

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Bone Morphogenetic Protein-2 (BMP-2) is one of the bone-growth regulatory factors that belong to the transforming growth factor-beta (TGF-beta) superfamily of proteins. BMPs are synthesized as large precursor molecules, which are cleaved by proteolytic enzymes. The active form of BMP-2 can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins.

Function : Induces cartilage and bone formation

Involvement in disease :

Subcellular location : Secreted

Protein Families : TGF-beta family

Tissue Specificity : Particularly abundant in lung, spleen and colon and in low but significant levels in heart, brain, placenta, liver, skeletal muscle, kidney, pancreas, prostate, ovary and small intestine.

Paythway : Hipposignalingpathway

Uniprot ID : P12643