Recombinant Human C-C motif chemokine 17 protein (CCL17) (Active)

Product Description

Recombinant Human C-C motif chemokine 17 protein (CCL17) (Active) is available at Gentaur for Next week Delivery.

Gene Name: CCL17,SCYA17,TARC

Alternative Names : CC chemokine TARC, Thymus and activation-regulated chemokine

Expression Region : 24-94aa

AA Sequence : ARGTNVGREC CLEYFKGAIP LRKLKTWYQT SEDCSRDAIV FVTVQGRAIC SDPNNKRVKN AVKYLQSLER S

Sequence Info : Full Length of Mature Protein

Tag Info : Tag-Free

Theoretical MW : 8.1 kDa

Storage Buffer : Lyophilized from a 0.2 ?m filtered 20mM PB, pH 7.4, 150mM NaCl

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration range of 1.0-10 ng/ml.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Immunology

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4. {ECO:0000269|PubMed:10540332}.

Function : Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4.

Involvement in disease :

Subcellular location : Secreted

Protein Families : Intercrine beta (chemokine CC) family

Tissue Specificity : Expressed at high levels in thymus and at low levels in the lung, colon and small intestine.

Paythway : Chemokinesignalingpathway

Uniprot ID : Q92583