Recombinant Human Caspase-5 (CASP5), partial

Product Description

Recombinant Human Caspase-5 (CASP5), partial is available at Gentaur for Next week Delivery.

Gene Name: CASP5

Alternative Names : ICE(rel)-III Protease ICH-3 Protease TY Cleaved into the following 2 chains: Caspase-5 subunit p20 Caspase-5 subunit p10

Expression Region : 137-327aa

AA Sequence : DQKITSVKPLLQIEAGPPESAESTNILKLCPREEFLRLCKKNHDEIYPIKKREDRRRLALIICNTKFDHLPARNGAHYDIVGMKRLLQGLGYTVVDEKNLTARDMESVLRAFAARPEHKSSDSTFLVLMSHGILEGICGTAHKKKKPDVLLYDTIFQIFNNRNCLSLKDKPKVIIVQACRGEKHGELWVRD

Sequence Info : Partial

Tag Info : N-terminal 6xHis-tagged

Theoretical MW : 23.8 kDa

Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Endotoxin Level : Not tested-

Biological Activity : Not tested

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Cell Biology

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Mediator of programmed cell death (apoptosis).

Function : Mediator of programmed cell death (apoptosis). During non-canonical inflammasome activation, cuts CGAS and may play a role in the regulation of antiviral innate immune activation

Involvement in disease :

Subcellular location :

Protein Families : Peptidase C14A family

Tissue Specificity : Expressed in barely detectable amounts in most tissues except brain, highest levels being found in lung, liver and skeletal muscle.

Paythway : NOD-likereceptorsignalingpathway

Uniprot ID : P51878