Recombinant Human Collagen alpha-1 protein (COL15A1) (Active)

Product Description

Recombinant Human Collagen alpha-1 protein (COL15A1) (Active) is available at Gentaur for Next week Delivery.

Gene Name: COL15A1

Alternative Names : XV, Related to endostatin, Restin-I,; Restin-2 Restin-II,; Restin-3 Restin-III

Expression Region : 1212-1388aa

AA Sequence : NYEKPALHLA ALNMPFSGDI RADFQCFKQA RAAGLLSTYR AFLSSHLQDL STIVRKAERY SLPIVNLKGQ VLFNNWDSIF SGHGGQFNMH IPIYSFDGRD IMTDPSWPQK VIWHGSSPHG VRLVDNYCEA WRTADTAVTG LASPLSTGKI LDQKAYSCAN RLIVLCIENS FMTDARK

Sequence Info : Partial

Tag Info : Tag-Free

Theoretical MW : 19.8 kDa

Storage Buffer : Lyophilized from a 0.2 ?m filtered PBS, pH 7.4

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The ED50 as determined by inhibiting the FGF basic-dependent proliferation of HUVEC migration is less than 2.0 µg/mL in the presence of Anti- Human Endostatin Polyclonal Antibody.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Cancer

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle. {ECO:0000269|PubMed:10049780}.; Restin potently inhibits angiogenesis. {ECO:0000250}.

Function : Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle.

Involvement in disease :

Subcellular location : Secreted, extracellular space, extracellular matrix

Protein Families : Multiplexin collagen family

Tissue Specificity : Expressed predominantly in internal organs such as adrenal gland, pancreas and kidney.

Paythway :

Uniprot ID : P39059