Recombinant Human Endophilin-A2 (SH3GL1)

Product Description

Recombinant Human Endophilin-A2 (SH3GL1) is available at Gentaur for Next week Delivery.

Gene Name: SH3GL1

Alternative Names : EEN fusion partner of MLL (Endophilin-2) (Extra eleven-nineteen leukemia fusion gene protein) (EEN) (SH3 domain protein 2B) (SH3 domain-containing GRB2-like protein 1 CNSA1) (SH3D2B)

Expression Region : 1-368aa

AA Sequence : MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVLARTIEYLQPNPASRAKLTMLNTVSKIRGQVKNPGYPQSEGLLGECMIRHGKELGGESNFGDALLDAGESMKRLAEVKDSLDIEVKQNFIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYKKKRQGKIPDEELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQILDELAEKLKRRMREASSRPKREYKPKPREPFDLGEPEQSNGGFPCTTAPKIAASSSFRSSDKPIRTPSRSMPPLDQPSCKALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDGQSGFFPLSYVEVLVPLPQ

Sequence Info : Full Length

Tag Info : N-terminal 10xHis-tagged

Theoretical MW : 45.0 kDa

Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Endotoxin Level : Not tested-

Biological Activity : Not tested

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Cell Biology

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Implicated in endocytosis. May recruit other proteins to membranes with high curvature

Function : Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity).

Involvement in disease : In some cases of acute leukemia, a translocation results in the formation of a KMT2A/MLL1-EEN fusion gene.

Subcellular location : Cytoplasm, Early endosome membrane, Peripheral membrane protein, Cell projection, podosome

Protein Families : Endophilin family

Tissue Specificity : Ubiquitous. Higher expression in pancreas, placenta, prostate, testis and uterus.

Paythway : Endocytosis

Uniprot ID : Q99961