Product Description
Recombinant Human Epigen protein (EPGN) (Active) is available at Gentaur for Next week Delivery.
Gene Name: EPGN,UNQ3072/PRO9904
Alternative Names : Epithelial mitogen,
Expression Region : 24-95aa
AA Sequence : AVTVTPPITA QQADNIEGPI ALKFSHLCLE DHNSYCINGA CAFHHELEKA ICRCFTGYTG ERCEHLTLTS YA
Sequence Info : Partial of Isoform 2
Tag Info : Tag-Free
Theoretical MW : 7.9 kDa
Storage Buffer : Lyophilized from a 0.2 µm filtered PBS, pH 7.4
Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-
Biological Activity : The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 300 ng/ml, corresponding to a specific activity of ? 3.3 × 103 IU/mg.
Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
Research Area : Cancer
Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance : Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases. {ECO:0000269|PubMed:15611079}.
Function : Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases.
Involvement in disease :
Subcellular location : Isoform 1: Membrane, Single-pass type I membrane protein, SUBCELLULAR LOCATION: Isoform 2: Membrane, Single-pass type I membrane protein, SUBCELLULAR LOCATION: Isoform 3: Secreted, SUBCELLULAR LOCATION: Isoform 4: Secreted, SUBCELLULAR LOCATION: Isoform 5: Secreted, SUBCELLULAR LOCATION: Isoform 6: Secreted
Protein Families :
Tissue Specificity :
Paythway :
Uniprot ID : Q6UW88