Recombinant Human Ferritin heavy chain (FTH1)

Product Description

Recombinant Human Ferritin heavy chain (FTH1) is available at Gentaur for Next week Delivery.

Gene Name: FTH1

Alternative Names : Cysteine-rich protein TTG-1LIM domain only protein 1;LMO-1T-cell translocation protein 1

Expression Region : 2-183aa

AA Sequence : TTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSDNES

Sequence Info : Full Length of Mature Protein

Tag Info : N-terminal GST-tagged

Theoretical MW : 48.1 kDa

Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Endotoxin Level : Not tested-

Biological Activity : Not tested

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Metabolism

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : May be involved in gene regulation within neural lineage cells potentially by direct DNA binding or by binding to other transcription factors.

Function : Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).

Involvement in disease : Hemochromatosis 5 (HFE5)

Subcellular location :

Protein Families : Ferritin family

Tissue Specificity : Expressed in the liver.

Paythway : Necroptosis

Uniprot ID : P02794