Recombinant Human Fibroblast growth factor 17 protein (FGF17) (Active)

Product Description

Recombinant Human Fibroblast growth factor 17 protein (FGF17) (Active) is available at Gentaur for Next week Delivery.

Gene Name: FGF17,UNQ161/PRO187

Alternative Names : FGF-17,

Expression Region : 23-216aa

AA Sequence : M+TQGENHPSP NFNQYVRDQG AMTDQLSRRQ IREYQLYSRT SGKHVQVTGR RISATAEDGN KFAKLIVETD TFGSRVRIKG AESEKYICMN KRGKLIGKPS GKSKDCVFTE IVLENNYTAF QNARHEGWFM AFTRQGRPRQ ASRSRQNQRE AHFIKRLYQG QLPFPNHAEK QKQFEFVGSA PTRRTKRTRR PQPLT

Sequence Info : Full Length of Mature Protein

Tag Info : Tag-Free

Theoretical MW : 22.6 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered PBS, pH 7.4

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The ED50 as determined by a cell proliferation assay using murine balb/c 3T3 cells is less than 10 ng/ml, corresponding to a specific activity of ?1.0 × 105 IU/mg.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Cancer

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain. Required for normal brain development. {ECO:0000269|PubMed:16597617}.

Function : Plays an important role in the regulation of embryonic development and as signaling molecule in the induction and patterning of the embryonic brain. Required for normal brain development.

Involvement in disease : Hypogonadotropic hypogonadism 20 with or without anosmia (HH20)

Subcellular location : Secreted

Protein Families : Heparin-binding growth factors family

Tissue Specificity : Preferentially expressed in the embryonic brain.

Paythway : MAPKsignalingpathway

Uniprot ID : O60258