Recombinant Human Fibroblast growth factor 21 protein (FGF21) (Active)

Product Description

Recombinant Human Fibroblast growth factor 21 protein (FGF21) (Active) is available at Gentaur for Next week Delivery.

Gene Name: FGF21,UNQ3115/PRO10196

Alternative Names : FGF-21,

Expression Region : 29-209aa

AA Sequence : HPIPDSSPLL QFGGQVRQRY LYTDDAQQTE AHLEIREDGT VGGAADQSPE SLLQLKALKP GVIQILGVKT SRFLCQRPDG ALYGSLHFDP EACSFRELLL EDGYNVYQSE AHGLPLHLPG NKSPHRDPAP RGPARFLPLP GLPPALPEPP GILAPQPPDV GSSDPLSMVG PSQGRSPSYA S

Sequence Info : Full Length of Mature Protein

Tag Info : Tag-Free

Theoretical MW : 19.4 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered PBS, pH 7.4

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The ED50 as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 0.5 ?g/ml, corresponding to a specific activity of ? 2.0 × 103 IU/mg in the presence of 5 µg/ml of rMuKlotho-? and 10 ?g/ml of heparin.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Cancer

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. {ECO:0000269|PubMed:15902306, ECO:0000269|PubMed:17623664}.

Function : Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB.

Involvement in disease :

Subcellular location : Secreted

Protein Families : Heparin-binding growth factors family

Tissue Specificity :

Paythway : MAPKsignalingpathway

Uniprot ID : Q9NSA1