Recombinant Human Fibroblast growth factor 7 protein (FGF7) (Active)

Product Description

Recombinant Human Fibroblast growth factor 7 protein (FGF7) (Active) is available at Gentaur for Next week Delivery.

Gene Name: FGF7,KGF

Alternative Names : FGF-7, HBGF-7, Keratinocyte growth factor

Expression Region : 32-194aa

AA Sequence : CNDMTPEQMA TNVNCSSPER HTRSYDYMEG GDIRVRRLFC RTQWYLRIDK RGKVKGTQEM KNNYNIMEIR TVAVGIVAIK GVESEFYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY ASAKWTHNGG EMFVALNQKG IPVRGKKTKK EQKTAHFLPM AIT

Sequence Info : Full Length of Mature Protein

Tag Info : Tag-Free

Theoretical MW : 18.9 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered 20 mM PB, 0.5 M NaCl, pH 8.0

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The ED50 as determined by thymidine uptake assay using FGF-receptors transfected BaF3 cells is less than 10 ng/ml, corresponding to a specific activity of ? 1.0 × 105 IU/mg.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Cancer

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation. {ECO:0000269|PubMed:16597617, ECO:0000269|PubMed:8663044}.

Function : Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation.

Involvement in disease :

Subcellular location : Secreted

Protein Families : Heparin-binding growth factors family

Tissue Specificity : Epithelial cell.

Paythway : MAPKsignalingpathway

Uniprot ID : P21781