Recombinant Human Fms-related tyrosine kinase 3 ligand protein (FLT3LG) (Active)

Product Description

Recombinant Human Fms-related tyrosine kinase 3 ligand protein (FLT3LG) (Active) is available at Gentaur for Next week Delivery.

Gene Name: FLT3LG

Alternative Names : Flt3 ligand, SL cytokine

Expression Region : 27-181aa

AA Sequence : TQDCSFQHSP ISSDFAVKIR ELSDYLLQDY PVTVASNLQD EELCGGLWRL VLAQRWMERL KTVAGSKMQG LLERVNTEIH FVTKCAFQPP PSCLRFVQTN ISRLLQETSE QLVALKPWIT RQNFSRCLEL QCQPDSSTLP PPWSPRPLEA TAPTA

Sequence Info : Partial

Tag Info : Tag-Free

Theoretical MW : 17.6 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered PBS, pH 7.0

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The ED50 as determined by a cell proliferation assay using human AML5 cells is less than 1.0 ng/ml, corresponding to a specific activity of ? 1.0 × 106 IU/mg.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Immunology

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.

Function : Stimulates the proliferation of early hematopoietic cells by activating FLT3. Synergizes well with a number of other colony stimulating factors and interleukins.

Involvement in disease :

Subcellular location : Isoform 1: Cell membrane, Single-pass type I membrane protein, SUBCELLULAR LOCATION: Isoform 2: Secreted

Protein Families :

Tissue Specificity :

Paythway : MAPKsignalingpathway

Uniprot ID : P49771