Recombinant Human FXYD domain-containing ion transport regulator 3 (FXYD3), partial

Product Description

Recombinant Human FXYD domain-containing ion transport regulator 3 (FXYD3), partial is available at Gentaur for Next week Delivery.

Gene Name: FXYD3

Alternative Names : Chloride conductance inducer protein Mat-8 (Mammary tumor 8 kDa protein) (Phospholemman-like) (Sodium/potassium-transporting ATPase subunit FXYD3) (MAT8) (PLML)

Expression Region : 21-38aa

AA Sequence : NDLEDKNSPFYYDWHSLQ

Sequence Info : Partial

Tag Info : N-terminal 6xHis-SUMO-tagged

Theoretical MW : 18.3 kDa

Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Endotoxin Level : Not tested-

Biological Activity : Not tested

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Cancer

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Associates with and regulates the activity of the sodium/potassium-transporting ATPase which transports Na+ out of the cell and K+ into the cell . Reduces glutathionylation of the NKA beta-1 subunit ATP1B1, thus reversing glutathionylation-mediated inhibition of ATP1B1. Induces a hyperpolarization-activated chloride current when expressed in Xenopus oocytes.

Function : Associates with and regulates the activity of the sodium/potassium-transporting ATPase (NKA) which transports Na(+) out of the cell and K(+) into the cell

Involvement in disease :

Subcellular location : Cell membrane, Single-pass type I membrane protein

Protein Families : FXYD family

Tissue Specificity : Isoform 1: Expressed mainly in differentiated cells (at protein level). Isoform 2: Expressed mainly in undifferentiated cells (at protein level).

Paythway :

Uniprot ID : Q14802