Recombinant Human Interleukin-10 protein (IL10) (Active)

Product Description

Recombinant Human Interleukin-10 protein (IL10) (Active) is available at Gentaur for Next week Delivery.

Gene Name: IL10

Alternative Names : IL-10, CSIF

Expression Region : 19-178aa

AA Sequence : SPGQGTQSEN SCTHFPGNLP NMLRDLRDAF SRVKTFFQMK DQLDNLLLKE SLLEDFKGYL GCQALSEMIQ FYLEEVMPQA ENQDPDIKAH VNSLGENLKT LRLRLRRCHR FLPCENKSKA VEQVKNAFNK LQEKGIYKAM SEFDIFINYI EAYMTMKIRN

Sequence Info : Full Length of Mature Protein

Tag Info : Tag-Free

Theoretical MW : 18.6 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered PBS, pH 7.4

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The ED50 as determined by a cell proliferation assay using murine MC/9-2 cells is less than 1 ng/ml, corresponding to a specific activity of ? 1.0 × 106 IU/mg.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Immunology

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.

Function : Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells.

Involvement in disease :

Subcellular location : Secreted

Protein Families : IL-10 family

Tissue Specificity : Produced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types.

Paythway : Jak-STATsignalingpathway

Uniprot ID : P22301