Recombinant Human Interleukin-17A protein (IL17A) (Active)

Product Description

Recombinant Human Interleukin-17A protein (IL17A) (Active) is available at Gentaur for Next week Delivery.

Gene Name: IL17A,CTLA8,IL17

Alternative Names : IL-17, Cytotoxic T-lymphocyte-associated antigen 8, CTLA-8

Expression Region : 24-155aa

AA Sequence : GITIPRNPGC PNSEDKNFPR TVMVNLNIHN RNTNTNPKRS SDYYNRSTSP WNLHRNEDPE RYPSVIWEAK CRHLGCINAD GNVDYHMNSV PIQQEILVLR REPPHCPNSF RLEKILVSVG CTCVTPIVHH VA

Sequence Info : Full Length of Mature Protein

Tag Info : Tag-Free

Theoretical MW : 31.0 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered PBS, pH 7.4

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The ED50 as determined by inducing IL-6 secretion of murine NIH/3T3 cells is less than 7.5 ng/ml, corresponding to a specific activity of ? 1.3 × 105 IU/mg.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Immunology

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of ICAM1/intracellular adhesion molecule 1 in fibroblasts.

Function : Ligand for IL17RA and IL17RC

Involvement in disease :

Subcellular location : Secreted

Protein Families : IL-17 family

Tissue Specificity : Restricted to activated memory T-cells.

Paythway : IL-17signalingpathway

Uniprot ID : Q16552