Recombinant Human Interleukin-17B protein (IL17B) (Active)

Product Description

Recombinant Human Interleukin-17B protein (IL17B) (Active) is available at Gentaur for Next week Delivery.

Gene Name: IL17B,IL20,NIRF,ZCYTO7,UNQ516/PRO1031

Alternative Names : IL-17B, Interleukin-20, IL-20, Neuronal interleukin-17-related factor,

Expression Region : 21-180aa

AA Sequence : M+QPRSPKSKR KGQGRPGPLA PGPHQVPLDL VSRMKPYARM EEYERNIEEM VAQLRNSSEL AQRKCEVNLQ LWMSNKRSLS PWGYSINHDP SRIPVDLPEA RCLCLGCVNP FTMQEDRSMV SVPVFSQVPV RRRLCPPPPR TGPCRQRAVM ETIAVGCTCI F

Sequence Info : Full Length of Mature Protein

Tag Info : Tag-Free

Theoretical MW : 36.5 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered PBS, pH 7.4, with 0.1 % Tween-20 and 3 % Trehalose

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The ED50 as determined by inducing IL-8 secretion of human HepG2 cells is less than 1.0 ?g/ml, corresponding to a specific activity of ? 1000 IU/mg.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Immunology

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1.

Function : Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1.

Involvement in disease :

Subcellular location : Secreted

Protein Families : IL-17 family

Tissue Specificity : Expressed in adult pancreas, small intestine, stomach, spinal cord and testis. Less pronounced expression in prostate, colon mucosal lining, and ovary.

Paythway : IL-17signalingpathway

Uniprot ID : Q9UHF5