Recombinant Human Leukemia inhibitory factor protein (LIF) (Active)

Product Description

Recombinant Human Leukemia inhibitory factor protein (LIF) (Active) is available at Gentaur for Next week Delivery.

Gene Name: LIF,HILDA

Alternative Names : LIF, D factor, Melanoma-derived LPL inhibitor, MLPLI, Emfilermin

Expression Region : 23-202aa

AA Sequence : SPLPITPVNA TCAIRHPCHN NLMNQIRSQL AQLNGSANAL FILYYTAQGE PFPNNLDKLC GPNVTDFPPF HANGTEKAKL VELYRIVVYL GTSLGNITRD QKILNPSALS LHSKLNATAD ILRGLLSNVL CRLCSKYHVG HVDVTYGPDT SGKDVFQKKK LGCQLLGKYK QIIAVLAQAF

Sequence Info : Full Length of Mature Protein

Tag Info : Tag-Free

Theoretical MW : 19.7 kDa

Storage Buffer : Lyophilized from a 0.2 ?m filtered PBS, pH 7.4

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The ED50 as determined by the dose-dependent proliferation of human TF-1 cells is less than 0.1 ng/ml, corresponding to a specific activity of ? 1.0 × 107 IU/mg.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Immunology

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.

Function : LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.

Involvement in disease :

Subcellular location : Secreted

Protein Families : LIF/OSM family

Tissue Specificity :

Paythway : Jak-STATsignalingpathway

Uniprot ID : P15018