Product Description
Recombinant Human LIM domain-binding protein 3 (LDB3) is available at Gentaur for Next week Delivery.
Gene Name: LDB3
Alternative Names : Protein cypher Z-band alternatively spliced PDZ-motif protein
Expression Region : 1-283aa
AA Sequence : MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVNSPANADYQERFNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSDFSGSLPIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSRERFETERNSPRFAKLRNWHHGLSAQILNVKS
Sequence Info : Full Length of Isoform 6
Tag Info : N-terminal GST-tagged
Theoretical MW : 58 kDa
Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Endotoxin Level : Not tested-
Biological Activity : Not tested
Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
Research Area : Signal Transduction
Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance : May function as an adapter in striated muscle to couple protein kinase C-mediated signaling via its LIM domains to the cytoskeleton.
Function : May function as an adapter in striated muscle to couple protein kinase C-mediated signaling via its LIM domains to the cytoskeleton.
Involvement in disease : Cardiomyopathy, dilated 1C, with or without left ventricular non-compaction (CMD1C); Left ventricular non-compaction 3 (LVNC3); Myopathy, myofibrillar, 4 (MFM4)
Subcellular location : Cytoplasm, perinuclear region, Cell projection, pseudopodium, Cytoplasm, cytoskeleton, Cytoplasm, myofibril, sarcomere, Z line
Protein Families :
Tissue Specificity : Expressed primarily in skeletal muscle and to a lesser extent in heart. Also detected in brain and placenta.
Paythway :
Uniprot ID : O75112