Recombinant Human Mitochondrial fission factor (MFF), partial

Product Description

Recombinant Human Mitochondrial fission factor (MFF), partial is available at Gentaur for Next week Delivery.

Gene Name: MFF

Alternative Names : C2orf33

Expression Region : 1-322aa

AA Sequence : MSKGTSSDTSLGRVSRAAFPSPTAAEMAEISRIQYEMEYTEGISQRMRVPEKLKVAPPNADLEQGFQEGVPNASVIMQVPERIVVAGNNEDVSFSRPADLDLIQSTPFKPLALKTPPRVLTLSERPLDFLDLERPPTTPQNEEIRAVGRLKRERSMSENAVRQNGQLVRNDSLWHRSDSAPRNKISRFQAPISAPEYTVTPSPQQARVCPPHMLPEDGANLSSARGILSLIQSSTRRAYQQILDVLDENRRPVLRGGSAAATSNPHHDNVRYGISNIDTTIEGTSDDLTVVDAASLRRQIIKLNRRLQLLEEENKERAKREM

Sequence Info : Partial

Tag Info : N-terminal 6xHis-tagged

Theoretical MW : 39.9 kDa

Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Endotoxin Level : Not tested-

Biological Activity : Not tested

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Others

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles.

Function : Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles.

Involvement in disease : Encephalopathy due to defective mitochondrial and peroxisomal fission 2 (EMPF2)

Subcellular location : Mitochondrion outer membrane, Single-pass type IV membrane protein, Peroxisome, Cytoplasmic vesicle, secretory vesicle, synaptic vesicle

Protein Families : Tango11 family

Tissue Specificity : Highly expressed in heart, kidney, liver, brain, muscle, and stomach.

Paythway :

Uniprot ID : Q9GZY8