Recombinant Human N-myc proto-oncogene protein (MYCN)

Product Description

Recombinant Human N-myc proto-oncogene protein (MYCN) is available at Gentaur for Next week Delivery.

Gene Name: MYCN

Alternative Names : Class E basic helix-loop-helix protein 37;bHLHe37

Expression Region : 1-464aa

AA Sequence : MPSCSTSTMPGMICKNPDLEFDSLQPCFYPDEDDFYFGGPDSTPPGEDIWKKFELLPTPPLSPSRGFAEHSSEPPSWVTEMLLENELWGSPAEEDAFGLGGLGGLTPNPVILQDCMWSGFSAREKLERAVSEKLQHGRGPPTAGSTAQSPGAGAASPAGRGHGGAAGAGRAGAALPAELAHPAAECVDPAVVFPFPVNKREPAPVPAAPASAPAAGPAVASGAGIAAPAGAPGVAPPRPGGRQTSGGDHKALSTSGEDTLSDSDDEDDEEEDEEEEIDVVTVEKRRSSSNTKAVTTFTITVRPKNAALGPGRAQSSELILKRCLPIHQQHNYAAPSPYVESEDAPPQKKIKSEASPRPLKSVIPPKAKSLSPRNSDSEDSERRRNHNILERQRRNDLRSSFLTLRDHVPELVKNEKAAKVVILKKATEYVHSLQAEEHQLLLEKEKLQARQQQLLKKIEHARTC

Sequence Info : Full Length

Tag Info : N-terminal 6xHis-tagged

Theoretical MW : 51.6 kDa

Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Endotoxin Level : Not tested-

Biological Activity : Not tested

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Cancer

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : May function as a transcription factor.

Function : Positively regulates the transcription of MYCNOS in neuroblastoma cells.

Involvement in disease : Feingold syndrome 1 (FGLDS1)

Subcellular location : Nucleus

Protein Families :

Tissue Specificity : Expressed in the neuronal cells of the cerebrum, neuroblastomas and thyroid tumors (at protein level).

Paythway :

Uniprot ID : P04198