Recombinant Human natriuretic peptide B (NPPB), partial

Product Description

Recombinant Human natriuretic peptide B (NPPB), partial is available at Gentaur for Next week Delivery.

Gene Name: NPPB

Alternative Names : Gamma-brain natriuretic peptide

Expression Region : 37-71aa

AA Sequence : DLETSGLQEQRNHLQGKLSELQVEQTSLEPLQESP

Sequence Info : Partial

Tag Info : N-terminal GST-tagged

Theoretical MW : 31 kDa

Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Endotoxin Level : Not tested-

Biological Activity : Not tested

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Signal Transduction

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.

Function : Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.

Involvement in disease :

Subcellular location : Secreted

Protein Families : Natriuretic peptide family

Tissue Specificity : Brain and also in atria, but at much lower levels than ANP.

Paythway : cGMP-PKGsignalingpathway

Uniprot ID : P16860