Recombinant Human Neutrophil elastase (ELANE)

Product Description

Recombinant Human Neutrophil elastase (ELANE) is available at Gentaur for Next week Delivery.

Gene Name: ELANE

Alternative Names : Bone marrow serine protease;Elastase-2Human leukocyte elastase;HLEMedullasin;PMN elastase

Expression Region : 30-267aa

AA Sequence : IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSEDNPCPHPRDPDPASRTH

Sequence Info : Full Length of Mature Protein

Tag Info : N-terminal 6xHis-tagged

Theoretical MW : 27.6 kDa

Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Endotoxin Level : Not tested-

Biological Activity : Not tested

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Signal Transduction

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chotaxis.

Function : Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis.

Involvement in disease : Cyclic haematopoiesis (CH); Neutropenia, severe congenital 1, autosomal dominant (SCN1)

Subcellular location :

Protein Families : Peptidase S1 family, Elastase subfamily

Tissue Specificity : Bone marrow cells.

Paythway :

Uniprot ID : P08246