Recombinant Human Parathyroid hormone protein (PTH),15N Stable Isotope Labeled (Active)

Product Description

Recombinant Human Parathyroid hormone protein (PTH),15N Stable Isotope Labeled (Active) is available at Gentaur for Next week Delivery.

Gene Name: PTH

Alternative Names : PTH, Parathyrin

Expression Region : 32-115aa

AA Sequence : SVSEIQLMHN LGKHLNSMER VEWLRKKLQD VHNFVALGAP LAPRDAGSQR PRKKEDNVLV ESHEKSLGEA DKADVNVLTK AKSQ

Sequence Info : Full Length of Mature Protein

Tag Info : Tag-Free

Theoretical MW : 9.5 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered PBS, pH 7.4

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The ED50 as determined by its ability to induce cAMP accumulation in murine MC3T3E1 cells is less than 50 ng/ml, corresponding to a specific activity of ? 2.0 × 104 IU/mg.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Signal Transduction

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. {ECO:0000269|PubMed:21076856}.

Function : PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.

Involvement in disease : Hypoparathyroidism, familial isolated (FIH)

Subcellular location : Secreted

Protein Families : Parathyroid hormone family

Tissue Specificity :

Paythway :

Uniprot ID : P01270