Recombinant Human Plasminogen activator inhibitor 2 protein (SERPINB2) (Active)

Product Description

Recombinant Human Plasminogen activator inhibitor 2 protein (SERPINB2) (Active) is available at Gentaur for Next week Delivery.

Gene Name: SERPINB2,PAI2,PLANH2

Alternative Names : PAI-2, Placental plasminogen activator inhibitor, Serpin B2, Urokinase inhibitor,

Expression Region : 1-415aa

AA Sequence : MEDLCVANTL FALNLFKHLA KASPTQNLFL SPWSISSTMA MVYMGSRGST EDQMAKVLQF NEVGANAVTP MTPENFTSCG FMQQIQKGSY PDAILQAQAA DKIHSSFRSL SSAINASTGN YLLESVNKLF GEKSASFREE YIRLCQKYYS SEPQAVDFLE CAEEARKKIN SWVKTQTKGK IPNLLPEGSV DGDTRMVLVN AVYFKGKWKT PFEKKLNGLY PFRVNSAQRT PVQMMYLREK LNIGYIEDLK AQILELPYAG DVSMFLLLPD EIADVSTGLE LLESEITYDK LNKWTSKDKM AEDEVEVYIP QFKLEEHYEL RSILRSMGME DAFNKGRANF SGMSERNDLF LSEVFHQAMV DVNEEGTEAA AGTGGVMTGR TGHGGPQFVA DHPFLFLIMH KITNCILFFG RFSSP

Sequence Info : Full Length

Tag Info : Tag-Free

Theoretical MW : 46.6 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered 20 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1 mM Cysteine, with 5 % Trehalose

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The biologically active was determined by its inhibitory effect against single chain tPA induced cleavage of a chromogenic substrate in Imidazole Buffer at 37 °C. Half maximal inhibition against 1.0 ?g/ml of single chain tPA was at a concentration of 1.0 ?g/ml.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Immunology

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.

Function : Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell-derived PAI-1.

Involvement in disease :

Subcellular location : Cytoplasm, Secreted, extracellular space

Protein Families : Serpin family, Ov-serpin subfamily

Tissue Specificity :

Paythway : Complementandcoagulationcascades

Uniprot ID : P05120