Recombinant Human Pleckstrin homology domain-containing family F member 2 (PLEKHF2)

Product Description

Recombinant Human Pleckstrin homology domain-containing family F member 2 (PLEKHF2) is available at Gentaur for Next week Delivery.

Gene Name: PLEKHF2

Alternative Names : Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains

Expression Region : 1-249aa

AA Sequence : MVDRLANSEANTRRISIVENCFGAAGQPLTIPGRVLIGEGVLTKLCRKKPKARQFFLFNDILVYGNIVIQKKKYNKQHIIPLENVTIDSIKDEGDLRNGWLIKTPTKSFAVYAATATEKSEWMNHINKCVTDLLSKSGKTPSNEHAAVWVPDSEATVCMRCQKAKFTPVNRRHHCRKCGFVVCGPCSEKRFLLPSQSSKPVRICDFCYDLLSAGDMATCQPARSDSYSQSLKSPLNDMSDDDDDDDSSD

Sequence Info : Full Length

Tag Info : N-terminal GST-tagged

Theoretical MW : 54.8 kDa

Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Endotoxin Level : Not tested-

Biological Activity : Not tested

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Cell Biology

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis

Function : May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis

Involvement in disease :

Subcellular location : Early endosome membrane, Peripheral membrane protein, Endoplasmic reticulum

Protein Families :

Tissue Specificity : Expressed in placenta, ovary and small intestine, as well as in heart and pancreas. Also expressed in peripheral blood mononuclear cells and dendritic cells.

Paythway :

Uniprot ID : Q9H8W4