Product Description
Recombinant Human Protein NOV homolog protein (NOV) (Active) is available at Gentaur for Next week Delivery.
Gene Name: NOV,CCN3,IGFBP9,NOVH
Alternative Names : NovH, Insulin-like growth factor-binding protein 9, IBP-9, IGF-binding protein 9, IGFBP-9
Expression Region : 28-357aa
AA Sequence : M+QVAATQRCP PQCPGRCPAT PPTCAPGVRA VLDGCSCCLV CARQRGESCS DLEPCDESSG LYCDRSADPS NQTGICTAVE GDNCVFDGVI YRSGEKFQPS CKFQCTCRDG QIGCVPRCQL DVLLPEPNCP APRKVEVPGE CCEKWICGPD EEDSLGGLTL AAYRPEATLG VEVSDSSVNC IEQTTEWTAC SKSCGMGFST RVTNRNRQCE MLKQTRLCMV RPCEQEPEQP TDKKGKKCLR TKKSLKAIHL QFKNCTSLHT YKPRFCGVCS DGRCCTPHNT KTIQAEFQCS PGQIVKKPVM VIGTCTCHTN CPKNNEAFLQ ELELKTTRGK M
Sequence Info : Full Length of Mature Protein
Tag Info : Tag-Free
Theoretical MW : 36.2 kDa
Storage Buffer : Lyophilized from a 0.2 µm filtered PBS, pH 7.0
Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-
Biological Activity : The ED50 as determined by a cell proliferation assay using murine Balb/c 3T3 cells is less than 1.0 ?g/ml, corresponding to a specific activity of ? 1000 IU/mg.
Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
Research Area : Immunology
Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance : Immediate-early protein likely to play a role in cell growth regulation. {ECO:0000250}.
Function : Immediate-early protein playing a role in various cellular processes including proliferation, adhesion, migration, differentiation and survival
Involvement in disease :
Subcellular location : Secreted, Cytoplasm, Cell junction, gap junction
Protein Families : CCN family
Tissue Specificity : Expressed in endiothelial cells (at protein level) (PubMed:21063504). Expressed in bone marrow, thymic cells and nephroblastoma. Increased expression in Wilms tumor of the stromal type.
Paythway :
Uniprot ID : P48745