Recombinant Human Receptor-type tyrosine-protein phosphatase-like N (PTPRN), partial

Product Description

Recombinant Human Receptor-type tyrosine-protein phosphatase-like N (PTPRN), partial is available at Gentaur for Next week Delivery.

Gene Name: PTPRN

Alternative Names : Islet cell antigen 512 Short name: ICA 512 Islet cell autoantigen 3 PTP IA-2

Expression Region : 35-575aa

AA Sequence : VSAHGCLFDRRLCSHLEVCIQDGLFGQCQVGVGQARPLLQVTSPVLQRLQGVLRQLMSQGLSWHDDLTQYVISQEMERIPRLRPPEPRPRDRSGLAPKRPGPAGELLLQDIPTGSAPAAQHRLPQPPVGKGGAGASSSLSPLQAELLPPLLEHLLLPPQPPHPSLSYEPALLQPYLFHQFGSRDGSRVSEGSPGMVSVGPLPKAEAPALFSRTASKGIFGDHPGHSYGDLPGPSPAQLFQDSGLLYLAQELPAPSRARVPRLPEQGSSSRAEDSPEGYEKEGLGDRGEKPASPAVQPDAALQRLAAVLAGYGVELRQLTPEQLSTLLTLLQLLPKGAGRNPGGVVNVGADIKKTMEGPVEGRDTAELPARTSPMPGHPTASPTSSEVQQVPSPVSSEPPKAARPPVTPVLLEKKSPLGQSQPTVAGQPSARPAAEEYGYIVTDQKPLSLAAGVKLLEILAEHVHMSSGSFINISVVGPALTFRIRHNEQNLSLADVTQQAGLVKSELEAQTGLQILQTGVGQREEAAAVLPQTAHSTSPMR

Sequence Info : Partial

Tag Info : C-terminal 6xHis-Myc-tagged

Theoretical MW : 60.3 kDa

Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Endotoxin Level : Not tested-

Biological Activity : Not tested

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Signal Transduction

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Implicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2.

Function : Plays a role in vesicle-mediated secretory processes

Involvement in disease : Autoantigen in insulin-dependent diabetes mellitus (IDDM).

Subcellular location : Membrane, Single-pass type I membrane protein, Cytoplasmic vesicle, secretory vesicle membrane, Single-pass type I membrane protein, Perikaryon, Cell projection, axon, Cell junction, synapse, Cell membrane, Single-pass type I membrane protein, Endosome

Protein Families : Protein-tyrosine phosphatase family, Receptor class 8 subfamily

Tissue Specificity : Expression is restricted to neuroendocrine cells. Found in pancreas, brain and pituitary.

Paythway :

Uniprot ID : Q16849