Recombinant Human Transcription factor MafK (MAFK)

Product Description

Recombinant Human Transcription factor MafK (MAFK) is available at Gentaur for Next week Delivery.

Gene Name: MAFK

Alternative Names : Erythroid transcription factor NF-E2 p18 subunit

Expression Region : 1-156aa

AA Sequence : MTTNPKPNKALKVKKEAGENAPVLSDDELVSMSVRELNQHLRGLTKEEVTRLKQRRRTLKNRGYAASCRIKRVTQKEELERQRVELQQEVEKLARENSSMRLELDALRSKYEALQTFARTVARGPVAPSKVATTSVITIVKSTELSSTSVPFSAAS

Sequence Info : Full Length

Tag Info : N-terminal 10xHis-tagged and C-terminal Myc-tagged

Theoretical MW : 21.5 kDa

Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Endotoxin Level : Not tested-

Biological Activity : Not tested

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Epigenetics and Nuclear Signaling

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor.

Function : Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves

Involvement in disease :

Subcellular location : Nucleus

Protein Families : BZIP family, Maf subfamily

Tissue Specificity :

Paythway :

Uniprot ID : O60675