Recombinant Human Trefoil factor 3 protein (TFF3) (Active)

Product Description

Recombinant Human Trefoil factor 3 protein (TFF3) (Active) is available at Gentaur for Next week Delivery.

Gene Name: TFF3,ITF,TFI

Alternative Names : Intestinal trefoil factor, Polypeptide P1.B, hP1.B

Expression Region : 22-80aa

AA Sequence : EEYVGLSANQ CAVPAKDRVD CGYPHVTPKE CNNRGCCFDS RIPGVPWCFK PLQEAECTF

Sequence Info : Full Length of Mature Protein

Tag Info : Tag-Free

Theoretical MW : 13.2 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered 20 mM PB, pH 7.4, 150mM NaCl

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The ED50 as determined by a chemotaxis bioassay using human MCF-7 cells is less than 10 ?g/ml, corresponding to a specific activity of ? 100 IU/mg.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Signal Transduction

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen). {ECO:0000269|PubMed:11694446}.

Function : Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen).

Involvement in disease :

Subcellular location : Secreted, extracellular space, extracellular matrix, Cytoplasm

Protein Families :

Tissue Specificity : Expressed in goblet cells of the intestines and colon (at protein level). Expressed by goblet cells of small and large intestinal epithelia and also by the uterus. Also expressed in the hypothalamus where it is detected in paraventricular, periventricular and supraoptic nuclei (at protein level).

Paythway :

Uniprot ID : Q07654