Recombinant Human Tumor necrosis factor ligand superfamily member 10 (TNFSF10), partial

Product Description

Recombinant Human Tumor necrosis factor ligand superfamily member 10 (TNFSF10), partial is available at Gentaur for Next week Delivery.

Gene Name: TNFSF10

Alternative Names : Apo-2 ligand;Apo-2LTNF-related apoptosis-inducing ligand;Protein TRAIL; CD253

Expression Region : 39-281aa

AA Sequence : TNELKQMQDKYSKSGIACFLKEDDSYWDPNDEESMNSPCWQVKWQLRQLVRKMILRTSEETISTVQEKQQNISPLVRERGPQRVAAHITGTRGRSNTLSSPNSKNEKALGRKINSWESSRSGHSFLSNLHLRNGELVIHEKGFYYIYSQTYFRFQEEIKENTKNDKQMVQYIYKYTSYPDPILLMKSARNSCWSKDAEYGLYSIYQGGIFELKENDRIFVSVTNEHLIDMDHEASFFGAFLVG

Sequence Info : Extracellular Domain

Tag Info : N-terminal GST-tagged

Theoretical MW : 55.4 kDa

Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

Endotoxin Level : Not tested-

Biological Activity : Not tested

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Apoptosis

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.

Function : Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG

Involvement in disease :

Subcellular location : Membrane, Single-pass type II membrane protein

Protein Families : Tumor necrosis factor family

Tissue Specificity : Widespread; most predominant in spleen, lung and prostate.

Paythway : Apoptosis

Uniprot ID : P50591