Recombinant Human Tumor necrosis factor ligand superfamily member 9 protein (TNFSF9) (Active)

Product Description

Recombinant Human Tumor necrosis factor ligand superfamily member 9 protein (TNFSF9) (Active) is available at Gentaur for Next week Delivery.

Gene Name: TNFSF9

Alternative Names : 4-1BB ligand,

Expression Region : 71-254aa

AA Sequence : REGPELSPDD PAGLLDLRQG MFAQLVAQNV LLIDGPLSWY SDPGLAGVSL TGGLSYKEDT KELVVAKAGV YYVFFQLELR RVVAGEGSGS VSLALHLQPL RSAAGAAALA LTVDLPPASS EARNSAFGFQ GRLLHLSAGQ RLGVHLHTEA RARHAWQLTQ GATVLGLFRV TPEIPAGLPS PRSE

Sequence Info : Partial

Tag Info : Tag-Free

Theoretical MW : 19.4 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered PBS, pH 7.4

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The ED50 as determined by stimulation of IL­8 production using human PBMC is less than 10 ng/ml, corresponding to a specific activity of ? 1.0 × 105 IU/mg.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Cancer

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages. {ECO:0000269|PubMed:20032458}.

Function : Cytokine that binds to TNFRSF9. Induces the proliferation of activated peripheral blood T-cells. May have a role in activation-induced cell death (AICD). May play a role in cognate interactions between T-cells and B-cells/macrophages.

Involvement in disease :

Subcellular location : Membrane, Single-pass type II membrane protein

Protein Families : Tumor necrosis factor family

Tissue Specificity : Expressed in brain, placenta, lung, skeletal muscle and kidney.

Paythway :

Uniprot ID : P41273