Recombinant Human Tumor necrosis factor receptor superfamily member 13C protein (TNFRSF13C) (Active)

Product Description

Recombinant Human Tumor necrosis factor receptor superfamily member 13C protein (TNFRSF13C) (Active) is available at Gentaur for Next week Delivery.

Gene Name: TNFRSF13C,BAFFR,BR3

Alternative Names : B-cell-activating factor receptor, BAFF-R, BLyS receptor 3, CD antigen CD268,

Expression Region : 1-76aa

AA Sequence : MRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS PAPRTALQPQ ESVGAGAGEA ALPLPG

Sequence Info : Partial

Tag Info : Tag-Free

Theoretical MW : 7.8 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered 20 mM PB, pH 8.0, 500 mM NaCl

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The ED50 as determined by its ability to block BAFF induced mouse splenocyte survival is 1.0-5.0 µg/ml in the presence of 1.0 ?g/ml of rHuBAFF.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Cancer

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response. {ECO:0000269|PubMed:11591325, ECO:0000269|PubMed:12387744}.

Function : B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response.

Involvement in disease : Immunodeficiency, common variable, 4 (CVID4)

Subcellular location : Membrane, Single-pass type III membrane protein

Protein Families :

Tissue Specificity : Highly expressed in spleen and lymph node, and in resting B-cells. Detected at lower levels in activated B-cells, resting CD4+ T-cells, in thymus and peripheral blood leukocytes.

Paythway : NF-kappaBsignalingpathway

Uniprot ID : Q96RJ3