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Product Description
Recombinant Human Tyrosine-protein kinase JAK1 (JAK1), partial is available at Gentaur for Next week Delivery.
Gene Name: JAK1
Alternative Names : Janus kinase 1 Short name: JAK-1
Expression Region : 850-1154aa
AA Sequence : EQNPDIVSEKKPATEVDPTHFEKRFLKRIRDLGEGHFGKVELCRYDPEGDNTGEQVAVKSLKPESGGNHIADLKKEIEILRNLYHENIVKYKGICTEDGGNGIKLIMEFLPSGSLKEYLPKNKNKINLKQQLKYAVQICKGMDYLGSRQYVHRDLAARNVLVESEHQVKIGDFGLTKAIETDKEYYTVKDDRDSPVFWYAPECLMQSKFYIASDVWSFGVTLHELLTYCDSDSSPMALFLKMIGPTHGQMTVTRLVNTLKEGKRLPCPPNCPDEVYQLMRKCWEFQPSNRTSFQNLIEGFEALLK
Sequence Info : Partial
Tag Info : N-terminal 6xHis-tagged
Theoretical MW : 36.9 kDa
Storage Buffer : Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Endotoxin Level : Not tested-
Biological Activity : Not tested
Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.
Research Area : Cancer
Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.
Relevance : Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.
Function : Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway
Involvement in disease :
Subcellular location : Endomembrane system, Peripheral membrane protein
Protein Families : Protein kinase superfamily, Tyr protein kinase family, JAK subfamily
Tissue Specificity : Expressed at higher levels in primary colon tumors than in normal colon tissue. The expression level in metastatic colon tumors is comparable to the expression level in normal colon tissue.
Paythway : Jak-STATsignalingpathway
Uniprot ID : P23458
