Recombinant Mouse C-X-C motif chemokine 16 protein (Cxcl16) (Active)

Product Description

Recombinant Mouse C-X-C motif chemokine 16 protein (Cxcl16) (Active) is available at Gentaur for Next week Delivery.

Gene Name: Cxcl16,Srpsox

Alternative Names : Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein, Small-inducible cytokine B16, Transmembrane chemokine CXCL16

Expression Region : 27-114aa

AA Sequence : NQGSVAGSCS CDRTISSGTQ IPQGTLDHIR KYLKAFHRCP FFIRFQLQSK SVCGGSQDQW VRELVDCFER KECGTGHGKS FHHQKHLP

Sequence Info : Partial

Tag Info : Tag-Free

Theoretical MW : 9.9 kDa

Storage Buffer : Lyophilized from a 0.2 µm filtered PBS, pH 7.4

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The biological activity determined by a chemotaxis bioassay using murine lymphocytes is in a concentration of 20-1000 ng/ml.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Immunology

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo. Also acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis. {ECO:0000269|PubMed:11060282}.

Function : Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo. Also acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis.

Involvement in disease :

Subcellular location : Membrane, Single-pass type I membrane protein

Protein Families : Intercrine alpha (chemokine CxC) family

Tissue Specificity : Widely expressed. Not detected in purified B- and T-cells.

Paythway :

Uniprot ID : Q8BSU2