Recombinant Mouse Desert hedgehog protein (Dhh) (Active), partial

Product Description

Recombinant Mouse Desert hedgehog protein (Dhh) (Active), partial is available at Gentaur for Next week Delivery.

Gene Name: Dhh

Alternative Names : DHH,

Expression Region : 24-198aa

AA Sequence : IIGPGRGPVG RRRYVRKQLV PLLYKQFVPS MPERTLGASG PAEGRVTRGS ERFRDLVPNY NPDIIFKDEE NSGADRLMTE RCKERVNALA IAVMNMWPGV RLRVTEGWDE DGHHAQDSLH YEGRALDITT SDRDRNKYGL LARLAVEAGF DWVYYESRNH IHVSVKADNS LAVRAGG

Sequence Info : Partial

Tag Info : Tag-Free

Theoretical MW : 20.0 kDa

Storage Buffer : Lyophilized from a 0.2 ?m filtered PBS, pH 7.4,1 mM DTT, 0.05 % Tween-80

Endotoxin Level : Less than 1.0 EU/µg as determined by LAL method.-

Biological Activity : The ED50 as determined by its ability to induce alkaline phosphatase production by murine MC3T3­E1 cells is 5­20 ?g/ml.

Storage : Short term: -20°C; Long term: -80°C. Minimize freeze and thaw cycles.

Research Area : Stem Cells 

Restriction : For Research Use Only. Not for use in diagnostic procedures, drug use, or for administration to humans or animals.

Relevance : Intercellular signal essential for a variety of patterning events during development. May function as a spermatocyte survival factor in the testes. Essential for testes development.

Function : Intercellular signal essential for a variety of patterning events during development. May function as a spermatocyte survival factor in the testes. Essential for testes development.

Involvement in disease :

Subcellular location : Desert hedgehog protein N-product: Cell membrane, Lipid-anchor, Extracellular side, Note=The N-terminal peptide remains associated with the cell surface, SUBCELLULAR LOCATION: Desert hedgehog protein C-product: Secreted, extracellular space

Protein Families : Hedgehog family

Tissue Specificity : Expressed in adult testes. Not expressed in limb buds.

Paythway :

Uniprot ID : Q61488